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Is Turmeric a panacea

Our ancestors used Turmeric in many of our treatments. More over we use this as a colouring material in our traditional cooking. Curcumin is the active ingredient in Turmeric. The ability of curcumin to cure many diseases is being proved by scientists all over the world. Recently Dr. Radhakrishna Pillai and DR. Dharam P Chauhan of University of California, San Diego has dound that curcumin is a potent anticancer drug. It can kill different types of cancer cells. With his research he proved that curcumin can kill cancer cells irrespective of its origin or genetic make up. Recently he has published some of his results in the international journal Anticancer Research.

            In another study Dr. Pillai and his group of researchers proved that curcumin can control the up regulation of chemokines. Chemokines are a group of chemicals produced in our body, which will help us to combat many of the infections. Though they are useful compounds, at times they cause harm to our body. For example in organ transplantation the donor organ will elicit immune response in the recipient’s body and this will result in over production of selected chemokines and in turn lead to the rejection of the transplanted organ. Ability to control production of chemokines in our body is a major concern. The power of curcumin to control chemokine production has got profound effect in treating diseases like AIDS or autoimmune diseases or even in survival of organ transplants. At present Dr. Pillai is engaged in a research project unravelling the role of curcumin in the survival of transplanted organs. The results are promising. If this research is successful we would have an easy and cost effective way to achieve success in organ transplantation.

A new method to trace the effectiveness of cancer therapy

Recently Dr. Radhakrishna Pillai along with Dr. Eric Aboagye has designed a method to trace the efficacy of cancer therapy. In this method they use Positron Emission Tomography (PET) to see the effect of the drugs. This is a non invasive technique to study the effect of a drug in a patient. Patients respond to different drugs in different ways. Certain drugs works fine in some but not in others. We need a method to closely evaluate the effect of the drug in different patients. In the new method they use radiolabelled [18F]Fluorothymidine to trace the metabolism in the body. Since this method measures change in the metabolism of tumour, the sensitivity is very high. In real time we can see whether a drug is going to be effective in a patient or not. This research is conducted at the Department of Imaging Sciences of Imperial College London and is funded by Cancer Research UK.

Earlier in another study Dr. Pillai had designed a method to estimate the gene expression levels of different chemokine genes and proteins. By using this method we can study the change in the expression levels of these genes. This has got far reaching effect in the diagnosis and treatment of diseases like HIV and autoimmune diseases.

 
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